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Coupling of Ca(2+) and voltage activation in BK channels through the αB helix/voltage sensor interface
Large-conductance Ca(2+) and voltage-activated K(+) (BK) channels control membrane excitability in many cell types. BK channels are tetrameric. Each subunit is composed of a voltage sensor domain (VSD), a central pore-gate domain, and a large cytoplasmic domain (CTD) that contains the Ca(2+) sensors...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7321994/ https://ncbi.nlm.nih.gov/pubmed/32513714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908183117 |
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