Ion sensing in the RCK1 domain of BK channels

BK-type K(+) channels are activated by voltage and intracellular Ca(2+), which is important in modulating muscle contraction, neural transmission, and circadian pacemaker output. Previous studies suggest that the cytosolic domain of BK channels contains two different Ca(2+) binding sites, but the mo...

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Bibliografiske detaljer
Main Authors: Zhang, Guohui, Huang, Sheng-You, Yang, Junqiu, Shi, Jingyi, Yang, Xiao, Moller, Alyssa, Zou, Xiaoqin, Cui, Jianmin
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972974/
https://ncbi.nlm.nih.gov/pubmed/20937866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010124107
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