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Participation of the S4 voltage sensor in the Mg(2+)-dependent activation of large conductance (BK) K(+) channels
The S4 transmembrane segment is the primary voltage sensor in voltage-dependent ion channels. Its movement in response to changes in membrane potential leads to the opening of the activation gate, which is formed by a separate structural component, the S6 segment. Here we show in voltage-, Ca(2+)-,...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC193588/ https://ncbi.nlm.nih.gov/pubmed/12925732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1834300100 |
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