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Coupling between Voltage Sensor Activation, Ca(2+) Binding and Channel Opening in Large Conductance (BK) Potassium Channels
To determine how intracellular Ca(2+) and membrane voltage regulate the gating of large conductance Ca(2+)-activated K(+) (BK) channels, we examined the steady-state and kinetic properties of mSlo1 ionic and gating currents in the presence and absence of Ca(2+) over a wide range of voltage. The acti...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2229516/ https://ncbi.nlm.nih.gov/pubmed/12198087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.20028605 |
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