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Type I Interferons Are Essential in Controlling Neurotropic Coronavirus Infection Irrespective of Functional CD8 T Cells

Neurotropic coronavirus infection induces expression of both beta interferon (IFN-β) RNA and protein in the infected rodent central nervous system (CNS). However, the relative contributions of type I IFN (IFN-I) to direct, cell-type-specific virus control or CD8 T-cell-mediated effectors in the CNS...

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Detalhes bibliográficos
Main Authors: Ireland, Derek D. C., Stohlman, Stephen A., Hinton, David R., Atkinson, Roscoe, Bergmann, Cornelia C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2224360/
https://ncbi.nlm.nih.gov/pubmed/17928334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01794-07
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