CD4 T Cells Contribute to Virus Control and Pathology following Central Nervous System Infection with Neurotropic Mouse Hepatitis Virus

Replication of the neurotropic mouse hepatitis virus strain JHM (JHMV) is controlled primarily by CD8(+) T-cell effectors utilizing gamma interferon (IFN-γ) and perforin-mediated cytotoxicity. CD4(+) T cells provide an auxiliary function(s) for CD8(+) T-cell survival; however, their direct contribut...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Stohlman, Stephen A., Hinton, David R., Parra, Beatriz, Atkinson, Roscoe, Bergmann, Cornelia C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258904/
https://ncbi.nlm.nih.gov/pubmed/18094171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01762-07
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky