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CD4 T Cells Contribute to Virus Control and Pathology following Central Nervous System Infection with Neurotropic Mouse Hepatitis Virus

Replication of the neurotropic mouse hepatitis virus strain JHM (JHMV) is controlled primarily by CD8(+) T-cell effectors utilizing gamma interferon (IFN-γ) and perforin-mediated cytotoxicity. CD4(+) T cells provide an auxiliary function(s) for CD8(+) T-cell survival; however, their direct contribut...

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Bibliografische gegevens
Hoofdauteurs: Stohlman, Stephen A., Hinton, David R., Parra, Beatriz, Atkinson, Roscoe, Bergmann, Cornelia C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258904/
https://ncbi.nlm.nih.gov/pubmed/18094171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01762-07
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