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Memory CD4(+) T-Cell-Mediated Protection from Lethal Coronavirus Encephalomyelitis

The antiviral role of CD4(+) T cells in virus-induced pathologies of the central nervous system (CNS) has not been explored extensively. Control of neurotropic mouse hepatitis virus (JHMV) requires the collaboration of CD4(+) and CD8(+) T cells, with CD8(+) T cells providing direct perforin and gamm...

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Autori principali: Savarin, Carine, Bergmann, Cornelia C., Hinton, David R., Ransohoff, Richard M., Stohlman, Stephen A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593339/
https://ncbi.nlm.nih.gov/pubmed/18842712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01267-08
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