IFN-γ protects from lethal IL-17 mediated viral encephalomyelitis independent of neutrophils

BACKGROUND: The interplay between IFN-γ, IL-17 and neutrophils during CNS inflammatory disease is complex due to cross-regulatory factors affecting both positive and negative feedback loops. These interactions have hindered the ability to distinguish the relative contributions of neutrophils, Th1 an...

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Autori principali: Savarin, Carine, Stohlman, Stephen A, Hinton, David R, Ransohoff, Richard M, Cua, Daniel J, Bergmann, Cornelia C
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419086/
https://ncbi.nlm.nih.gov/pubmed/22642802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-104
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