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UBIQUITINATION OF β-ARRESTIN LINKS 7-TRANSMEMBRANE RECEPTOR ENDOCYTOSIS AND ERK ACTIVATION
β-arrestin2 and its ubiquitination play crucial roles in both internalization and signaling of seven-transmembrane receptors (7TMRs). To understand the connection between ubiquitination and β-arrestin’s endocytic and signaling functions, we generated a β-arrestin2 mutant that is defective in ubiquit...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2216744/ https://ncbi.nlm.nih.gov/pubmed/17666399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M700852200 |
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