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Activation and Tolerance in CD4(+) T Cells Reactive to an Immunoglobulin Variable Region

Antibody diversity creates an immunoregulatory challenge for T cells that must cooperate with B cells, yet discriminate between self and nonself. To examine the consequences of T cell reactions to the B cell receptor (BCR), we generated a transgenic (Tg) line of mice expressing a T cell receptor (TC...

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Detalhes bibliográficos
Main Authors: Snyder, Christopher M., Aviszus, Katja, Heiser, Ryan A., Tonkin, Daniel R., Guth, Amanda M., Wysocki, Lawrence J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213315/
https://ncbi.nlm.nih.gov/pubmed/15226360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031234
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