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Immunoglobulin heavy chain constant regions regulate immunity and tolerance to idiotypes of antibody variable regions
Particular syngeneic adjuvant-free monoclonal antibodies are immunogenic and elicit antibody responses against the variable region idiotypes (Ids). We here study how heavy-chain constant regions (C(H)) regulate immune responses to Ids of free, uncomplexed monoclonal antibodies. To this end, we selec...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124293/ https://ncbi.nlm.nih.gov/pubmed/12032327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052150899 |
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