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Aborted Germinal Center Reactions and B Cell Memory by Follicular T Cells Specific for a B Cell Receptor V Region Peptide

A fundamental problem in immunoregulation is how CD4(+) T cells react to immunogenic peptides derived from the V region of the BCR that are created by somatic mechanisms, presented in MHC II, and amplified to abundance by B cell clonal expansion during immunity. BCR neo Ags open a potentially danger...

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Détails bibliographiques
Auteurs principaux: Heiser, Ryan A., Snyder, Christopher M., Clair, James St., Wysocki, Lawrence J.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3133611/
https://ncbi.nlm.nih.gov/pubmed/21622866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002328
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