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T follicular helper cells in germinal center B cell selection and lymphomagenesis

Germinal centers (GCs) are confined anatomic regions where rapidly proliferating B cells undergo somatic mutation and selection and eventual differentiation into memory B cells or long-lived plasma cells. GCs are also the origin of malignancy, namely follicular lymphoma (FL), GC B cell-diffuse large...

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Detalhes bibliográficos
Publicado no:Immunol Rev
Main Authors: Mintz, Michelle A, Cyster, Jason G
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817257/
https://ncbi.nlm.nih.gov/pubmed/32412663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12860
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