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Sphingosine-1-phosphate receptor 2 is critical for follicular helper T cell retention in germinal centers

Follicular helper T (Tfh) cells access the B cell follicle to promote antibody responses and are particularly important for germinal center (GC) reactions. However, the molecular mechanisms of how Tfh cells are physically associated with GCs are incompletely understood. We report that the sphingosin...

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Detalhes bibliográficos
Main Authors: Moriyama, Saya, Takahashi, Noriko, Green, Jesse A., Hori, Shohei, Kubo, Masato, Cyster, Jason G., Okada, Takaharu
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076581/
https://ncbi.nlm.nih.gov/pubmed/24913235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131666
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