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Sphingosine-1-phosphate receptor 2 is critical for follicular helper T cell retention in germinal centers

Follicular helper T (Tfh) cells access the B cell follicle to promote antibody responses and are particularly important for germinal center (GC) reactions. However, the molecular mechanisms of how Tfh cells are physically associated with GCs are incompletely understood. We report that the sphingosin...

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Bibliografiske detaljer
Main Authors: Moriyama, Saya, Takahashi, Noriko, Green, Jesse A., Hori, Shohei, Kubo, Masato, Cyster, Jason G., Okada, Takaharu
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076581/
https://ncbi.nlm.nih.gov/pubmed/24913235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131666
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