Sphingosine-1-phosphate receptor 2 is critical for follicular helper T cell retention in germinal centers

Follicular helper T (Tfh) cells access the B cell follicle to promote antibody responses and are particularly important for germinal center (GC) reactions. However, the molecular mechanisms of how Tfh cells are physically associated with GCs are incompletely understood. We report that the sphingosin...

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Detalles Bibliográficos
Autores principales: Moriyama, Saya, Takahashi, Noriko, Green, Jesse A., Hori, Shohei, Kubo, Masato, Cyster, Jason G., Okada, Takaharu
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2014
Materias:
Brief Definitive Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076581/
https://ncbi.nlm.nih.gov/pubmed/24913235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131666
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