Sphingosine-1-phosphate receptor 2 is critical for follicular helper T cell retention in germinal centers

Follicular helper T (Tfh) cells access the B cell follicle to promote antibody responses and are particularly important for germinal center (GC) reactions. However, the molecular mechanisms of how Tfh cells are physically associated with GCs are incompletely understood. We report that the sphingosin...

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Dettagli Bibliografici
Autori principali: Moriyama, Saya, Takahashi, Noriko, Green, Jesse A., Hori, Shohei, Kubo, Masato, Cyster, Jason G., Okada, Takaharu
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2014
Soggetti:
Brief Definitive Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076581/
https://ncbi.nlm.nih.gov/pubmed/24913235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131666
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