Sphingosine-1-phosphate receptor 2 is critical for follicular helper T cell retention in germinal centers

Follicular helper T (Tfh) cells access the B cell follicle to promote antibody responses and are particularly important for germinal center (GC) reactions. However, the molecular mechanisms of how Tfh cells are physically associated with GCs are incompletely understood. We report that the sphingosin...

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Библиографические подробности
Главные авторы: Moriyama, Saya, Takahashi, Noriko, Green, Jesse A., Hori, Shohei, Kubo, Masato, Cyster, Jason G., Okada, Takaharu
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2014
Предметы:
Brief Definitive Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076581/
https://ncbi.nlm.nih.gov/pubmed/24913235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131666
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