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Dynamic signaling by T follicular helper cells during germinal center B cell selection

T follicular helper (T(FH)) cells select high-affinity, antibody-producing B cells for clonal expansion in germinal centers (GCs), but the nature of their interaction is not well defined. Using intravital imaging, we found that selection is mediated by large but transient contacts between T(FH) and...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Science
मुख्य लेखकों: Shulman, Ziv, Gitlin, Alexander D., Weinstein, Jason S., Lainez, Begoña, Esplugues, Enric, Flavell, Richard A., Craft, Joseph E., Nussenzweig, Michel C.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519234/
https://ncbi.nlm.nih.gov/pubmed/25170154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1257861
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