Follicular helper T cells progressively differentiate to regulate the germinal center response

Germinal center (GC) B cells undergo affinity selection, dependent upon interactions with CD4(+) follicular helper T (T(FH)) cells. We demonstrate that T(FH) cells progressed through transcriptionally and functionally distinct stages, providing differential signals for GC regulation. They initially...

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Detaylı Bibliyografya
Yayımlandı:Nat Immunol
Asıl Yazarlar: Weinstein, Jason S., Herman, Edward I., Lainez, Begoña, Licona-Limón, Paula, Esplugues, Enric, Flavell, Richard, Craft, Joe
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030190/
https://ncbi.nlm.nih.gov/pubmed/27573866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3554
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