Llwytho...
Clonal selection in the germinal center by regulated proliferation and hypermutation
During immune responses, B lymphocytes clonally expand and undergo secondary diversification of their immunoglobulin (Ig) genes in germinal centers (GCs)(1–4). High affinity B cells are expanded through iterative interzonal cycles of division and hypermutation in the GC dark zone (DZ) followed by mi...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Nature |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2014
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4271732/ https://ncbi.nlm.nih.gov/pubmed/24805232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13300 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|