A carregar...

Independent roles of switching and hypermutation in the development and persistence of B lymphocyte memory

Somatic hypermutation (SHM) and class switch recombination (CSR) increase the affinity and diversify the effector functions of antibodies during immune responses. Although SHM and CSR are fundamentally different, their independent roles in regulating B cell fate have been difficult to uncouple becau...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Gitlin, Alexander D., von Boehmer, Lotta, Gazumyan, Anna, Shulman, Ziv, Oliveira, Thiago Y., Nussenzweig, Michel C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838502/
https://ncbi.nlm.nih.gov/pubmed/26944202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.01.011
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!