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The Microanatomic Segregation of Selection by Apoptosis in the Germinal Center
B cells undergo rapid cell division and affinity maturation in anatomically distinct sites in lymphoid organs called germinal centers (GCs). Homeostasis is maintained in part by B-cell apoptosis. However, the precise contribution of apoptosis to GC biology and selection is not well defined. We devel...
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| 出版年: | Science |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5957278/ https://ncbi.nlm.nih.gov/pubmed/28935768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aao2602 |
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