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Self-tolerance checkpoints in CD4 T cells specific for a peptide derived from the B cell antigen receptor

Linked recognition of antigen by B and T lymphocytes is ensured in part by a state of tolerance acquired by CD4 T cells to germline-encoded sequences within the B cell antigen receptor (BCR). We sought to determine how such tolerance is attained when a peptide from the BCR variable (V) region is exp...

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Autores principales: Detanico, Thiago, Heiser, Ryan, Aviszus, Katja, Bonorino, Cristina B, Wysocki, Lawrence J
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124280/
https://ncbi.nlm.nih.gov/pubmed/21622865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002287
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