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Functionally Responsive Self-Reactive B Cells of Low-Affinity Express Reduced Levels of Surface IgM()

Somatic gene rearrangement generates a diverse repertoire of B cells, including B cell receptors (BCR) possessing a range of affinities for self-Ag. Newly generated B cells express high and relatively uniform amounts of surface IgM (sIgM), while follicular (FO) B cells express sIgM at widely varying...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Kirchenbaum, Greg A., St. Clair, James B., Detanico, Thiago, Aviszus, Katja, Wysocki, Lawrence J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984621/
https://ncbi.nlm.nih.gov/pubmed/24375379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344276
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