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Functionally Responsive Self-Reactive B Cells of Low-Affinity Express Reduced Levels of Surface IgM()
Somatic gene rearrangement generates a diverse repertoire of B cells, including B cell receptors (BCR) possessing a range of affinities for self-Ag. Newly generated B cells express high and relatively uniform amounts of surface IgM (sIgM), while follicular (FO) B cells express sIgM at widely varying...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3984621/ https://ncbi.nlm.nih.gov/pubmed/24375379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344276 |
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