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Blockade of self-reactive IgM significantly reduces injury in a murine model of acute myocardial infarction
AIMS: Coronary artery occlusion resulting in ischaemia/reperfusion (I/R) injury is a major cause of mortality in the western world. Circulating natural IgM has been shown to play a significant role in reperfusion injury, leading to the notion of a pathogenic response against self by the innate immun...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2920809/ https://ncbi.nlm.nih.gov/pubmed/20462867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq141 |
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