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Requirement for complement in antibody responses is not explained by the classic pathway activator IgM

Animals lacking complement factors C1q, C2, C3, or C4 have severely impaired Ab responses, suggesting a major role for the classic pathway. The classic pathway is primarily initiated by antigen–Ab complexes. Therefore, its role for primary Ab responses seems paradoxical because only low amounts of s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rutemark, Christian, Alicot, Elisabeth, Bergman, Anna, Ma, Minghe, Getahun, Andrew, Ellmerich, Stephan, Carroll, Michael C., Heyman, Birgitta
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203774/
https://ncbi.nlm.nih.gov/pubmed/21987785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109831108
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