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Requirement for complement in antibody responses is not explained by the classic pathway activator IgM
Animals lacking complement factors C1q, C2, C3, or C4 have severely impaired Ab responses, suggesting a major role for the classic pathway. The classic pathway is primarily initiated by antigen–Ab complexes. Therefore, its role for primary Ab responses seems paradoxical because only low amounts of s...
Tallennettuna:
| Päätekijät: | , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3203774/ https://ncbi.nlm.nih.gov/pubmed/21987785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109831108 |
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