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Critical role of the IgM Fc receptor in IgM homeostasis, B-cell survival, and humoral immune responses
IgM antibodies have been known for decades to enhance humoral immune responses in an antigen-specific fashion. This enhancement has been thought to be dependent on complement activation by IgM–antigen complexes; however, recent genetic studies render this mechanism unlikely. Here, we describe a like...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3479561/ https://ncbi.nlm.nih.gov/pubmed/22988094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210706109 |
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