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Functional Versatility of AGY Serine Codons in Immunoglobulin Variable Region Genes
In systemic autoimmunity, autoantibodies directed against nuclear antigens (Ags) often arise by somatic hypermutation (SHM) that converts AGT and AGC (AGY) Ser codons into Arg codons. This can occur by three different single-base changes. Curiously, AGY Ser codons are far more abundant in complement...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5118421/ https://ncbi.nlm.nih.gov/pubmed/27920779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00525 |
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