Multiple event activation of a generic prodrug trigger by antibody catalysis

Chemotherapeutic regimes are typically limited by nonspecific toxicity. To address this problem we have developed a broadly applicable drug-masking chemistry that operates in conjunction with a unique broad-scope catalytic antibody. This masking chemistry is applicable to a wide range of drugs becau...

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Detaylı Bibliyografya
Asıl Yazarlar: Shabat, Doron, Rader, Christoph, List, Benjamin, Lerner, Richard A., Barbas, Carlos F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 1999
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC22018/
https://ncbi.nlm.nih.gov/pubmed/10359815
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