Multiple event activation of a generic prodrug trigger by antibody catalysis
Chemotherapeutic regimes are typically limited by nonspecific toxicity. To address this problem we have developed a broadly applicable drug-masking chemistry that operates in conjunction with a unique broad-scope catalytic antibody. This masking chemistry is applicable to a wide range of drugs becau...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1999
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22018/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10359815/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.12.6925 |
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