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Strategy for Constructing Prodrug-Type Bispecific Antibodies Activated by Matrix Metalloproteinases

Given the high specific expression of matrix metalloproteinases in the solid tumor microenvironment, they serve as an ideal endogenous triggering mechanism for the tumor-selective activation of antibody drugs This paper systematically summarizes the construction strategies of pro-drug bispecific ant...

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Autore principale: Hao Yitong
Natura: Artigo
Lingua:Inglês
Pubblicazione: EDP Sciences 2026-01-01
Serie:BIO Web of Conferences
Accesso online:https://www.bio-conferences.org/articles/bioconf/pdf/2026/33/bioconf_icbnb2026_01002.pdf
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