Targeting Notch signaling in autoimmune and lymphoproliferative disease

Patients with autoimmune lymphoproliferative syndrome (ALPS) and systemic lupus erythematosis (SLE) have T-cell dysregulation and produce abnormal, activated T lymphocytes and an atypical peripheral T-cell population, termed double negative T cells (DNTs). T-cell functions, including DNT transition...

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Détails bibliographiques
Auteurs principaux: Teachey, David T., Seif, Alix E., Brown, Valerie I., Bruno, Marlo, Bunte, Ralph M., Chang, Yueh J., Choi, John K., Fish, Jonathan D., Hall, Junior, Reid, Gregor S., Ryan, Theresa, Sheen, Cecilia, Zweidler-McKay, Patrick, Grupp, Stephan A.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2008
Sujets:
Immunobiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200835/
https://ncbi.nlm.nih.gov/pubmed/17925488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-087353
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