Treatment with sirolimus results in complete responses in patients with autoimmune lymphoproliferative syndrome

We hypothesized that sirolimus, an mTOR inhibitor, may be effective in patients with autoimmune lymphoproliferative syndrome (ALPS) and treated patients who were intolerant to or failed other therapies. Four patients were treated for autoimmune cytopenias; all had a rapid complete or near complete r...

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Detalhes bibliográficos
Main Authors: Teachey, David T., Greiner, Robert, Seif, Alix, Attiyeh, Edward, Bleesing, Jack, Choi, John, Manno, Catherine, Rappaport, Eric, Schwabe, Dirk, Sheen, Cecilia, Sullivan, Kathleen E., Zhuang, Hongming, Wechsler, Daniel S., Grupp, Stephan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819393/
https://ncbi.nlm.nih.gov/pubmed/19208097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2009.07595.x
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