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Sirolimus is effective in relapsed/refractory autoimmune cytopenias: results of a prospective multi-institutional trial

Patients with autoimmune multilineage cytopenias are often refractory to standard therapies requiring chronic immunosuppression with medications with limited efficacy and high toxicity. We present data on 30 patients treated on a multicenter prospective clinical trial using sirolimus as monotherapy....

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Bride, Karen L., Vincent, Tiffaney, Smith-Whitley, Kim, Lambert, Michele P., Bleesing, Jack J., Seif, Alix E., Manno, Catherine S., Casper, James, Grupp, Stephan A., Teachey, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705607/
https://ncbi.nlm.nih.gov/pubmed/26504182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-07-657981
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