Targeting Notch signaling in autoimmune and lymphoproliferative disease

Patients with autoimmune lymphoproliferative syndrome (ALPS) and systemic lupus erythematosis (SLE) have T-cell dysregulation and produce abnormal, activated T lymphocytes and an atypical peripheral T-cell population, termed double negative T cells (DNTs). T-cell functions, including DNT transition...

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Hlavní autoři: Teachey, David T., Seif, Alix E., Brown, Valerie I., Bruno, Marlo, Bunte, Ralph M., Chang, Yueh J., Choi, John K., Fish, Jonathan D., Hall, Junior, Reid, Gregor S., Ryan, Theresa, Sheen, Cecilia, Zweidler-McKay, Patrick, Grupp, Stephan A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2008
Témata:
Immunobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200835/
https://ncbi.nlm.nih.gov/pubmed/17925488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-087353
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