Targeting Notch signaling in autoimmune and lymphoproliferative disease

Patients with autoimmune lymphoproliferative syndrome (ALPS) and systemic lupus erythematosis (SLE) have T-cell dysregulation and produce abnormal, activated T lymphocytes and an atypical peripheral T-cell population, termed double negative T cells (DNTs). T-cell functions, including DNT transition...

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Detalhes bibliográficos
Main Authors: Teachey, David T., Seif, Alix E., Brown, Valerie I., Bruno, Marlo, Bunte, Ralph M., Chang, Yueh J., Choi, John K., Fish, Jonathan D., Hall, Junior, Reid, Gregor S., Ryan, Theresa, Sheen, Cecilia, Zweidler-McKay, Patrick, Grupp, Stephan A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200835/
https://ncbi.nlm.nih.gov/pubmed/17925488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-087353
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