Targeting Notch signaling in autoimmune and lymphoproliferative disease

Patients with autoimmune lymphoproliferative syndrome (ALPS) and systemic lupus erythematosis (SLE) have T-cell dysregulation and produce abnormal, activated T lymphocytes and an atypical peripheral T-cell population, termed double negative T cells (DNTs). T-cell functions, including DNT transition...

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Hauptverfasser: Teachey, David T., Seif, Alix E., Brown, Valerie I., Bruno, Marlo, Bunte, Ralph M., Chang, Yueh J., Choi, John K., Fish, Jonathan D., Hall, Junior, Reid, Gregor S., Ryan, Theresa, Sheen, Cecilia, Zweidler-McKay, Patrick, Grupp, Stephan A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2008
Schlagworte:
Immunobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200835/
https://ncbi.nlm.nih.gov/pubmed/17925488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-087353
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