Targeting Notch signaling in autoimmune and lymphoproliferative disease

Patients with autoimmune lymphoproliferative syndrome (ALPS) and systemic lupus erythematosis (SLE) have T-cell dysregulation and produce abnormal, activated T lymphocytes and an atypical peripheral T-cell population, termed double negative T cells (DNTs). T-cell functions, including DNT transition...

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Autors principals: Teachey, David T., Seif, Alix E., Brown, Valerie I., Bruno, Marlo, Bunte, Ralph M., Chang, Yueh J., Choi, John K., Fish, Jonathan D., Hall, Junior, Reid, Gregor S., Ryan, Theresa, Sheen, Cecilia, Zweidler-McKay, Patrick, Grupp, Stephan A.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2008
Matèries:
Immunobiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200835/
https://ncbi.nlm.nih.gov/pubmed/17925488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-087353
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