טוען...
Platelet-VWF complexes are preferred substrates of ADAMTS13 under fluid shear stress
Endothelial cells secrete prothrombotic ultralarge von Willebrand factor (VWF) multimers, and the metalloprotease ADAMTS13 cleaves them into smaller, less dangerous multimers. This reaction is stimulated by tensile force applied to the VWF substrate, which may occur on cell surfaces or in the circul...
שמור ב:
| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society of Hematology
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2200832/ https://ncbi.nlm.nih.gov/pubmed/17901248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-093021 |
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