Llwytho...

Platelet-VWF complexes are preferred substrates of ADAMTS13 under fluid shear stress

Endothelial cells secrete prothrombotic ultralarge von Willebrand factor (VWF) multimers, and the metalloprotease ADAMTS13 cleaves them into smaller, less dangerous multimers. This reaction is stimulated by tensile force applied to the VWF substrate, which may occur on cell surfaces or in the circul...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shim, Kyuhwan, Anderson, Patricia J., Tuley, Elodee A., Wiswall, Erin, Evan Sadler, J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200832/
https://ncbi.nlm.nih.gov/pubmed/17901248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-093021
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