Extensive contacts between ADAMTS13 exosites and von Willebrand factor domain A2 contribute to substrate specificity

Lignende værker

• Exosite interactions contribute to tension-induced cleavage of von Willebrand factor by the antithrombotic ADAMTS13 metalloprotease
  af: Gao, Weiqiang, et al.
  Udgivet: (2006)
• Rearranging Exosites in Noncatalytic Domains Can Redirect the Substrate Specificity of ADAMTS Proteases
  af: Gao, Weiqiang, et al.
  Udgivet: (2012)
• Cleavage of ultralarge multimers of von Willebrand factor by C-terminal–truncated mutants of ADAMTS-13 under flow
  af: Tao, Zhenyin, et al.
  Udgivet: (2005)
• Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura
  af: Sadler, J. Evan
  Udgivet: (2008)
• Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor
  af: Akiyama, Masashi, et al.
  Udgivet: (2009)