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Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura

Discoveries during the past decade have revolutionized our understanding of idiopathic thrombotic thrombocytopenic purpura (TTP). Most cases in adults are caused by acquired autoantibodies that inhibit ADAMTS13, a metalloprotease that cleaves von Willebrand factor within nascent platelet-rich thromb...

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Bibliografski detalji
Glavni autor: Sadler, J. Evan
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435681/
https://ncbi.nlm.nih.gov/pubmed/18574040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-078170
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