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Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura

Discoveries during the past decade have revolutionized our understanding of idiopathic thrombotic thrombocytopenic purpura (TTP). Most cases in adults are caused by acquired autoantibodies that inhibit ADAMTS13, a metalloprotease that cleaves von Willebrand factor within nascent platelet-rich thromb...

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Hlavní autor: Sadler, J. Evan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435681/
https://ncbi.nlm.nih.gov/pubmed/18574040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-078170
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