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Von Willebrand factor, ADAMTS13, and thrombotic thrombocytopenic purpura
Discoveries during the past decade have revolutionized our understanding of idiopathic thrombotic thrombocytopenic purpura (TTP). Most cases in adults are caused by acquired autoantibodies that inhibit ADAMTS13, a metalloprotease that cleaves von Willebrand factor within nascent platelet-rich thromb...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2435681/ https://ncbi.nlm.nih.gov/pubmed/18574040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-078170 |
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