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Pathophysiology of thrombotic thrombocytopenic purpura

The discovery of a disintegrin-like and metalloproteinase with thrombospondin type 1 motif, member 13 (ADAMTS13) revolutionized our approach to thrombotic thrombocytopenic purpura (TTP). Inherited or acquired ADAMTS13 deficiency allows the unrestrained growth of microthrombi that are composed of von...

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Bibliographic Details
Published in:Blood
Main Author: Sadler, J. Evan
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5606001/
https://ncbi.nlm.nih.gov/pubmed/28768626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-04-636431
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