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Shiga toxin B subunits induce VWF secretion by human endothelial cells and thrombotic microangiopathy in ADAMTS13-deficient mice

Diarrhea–associated hemolytic uremic syndrome (D(+)HUS) is the most common cause of acute renal failure among children. Renal damage in D(+)HUS is caused by Shiga toxin (Stx), which is elaborated by Shigella dysenteriae and certain strains of Escherichia coli, in North America principally E coli O15...

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Hlavní autoři: Huang, Jing, Motto, David G., Bundle, David R., Sadler, J. Evan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981485/
https://ncbi.nlm.nih.gov/pubmed/20644116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-02-271957
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