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Shiga toxin B subunits induce VWF secretion by human endothelial cells and thrombotic microangiopathy in ADAMTS13-deficient mice
Diarrhea–associated hemolytic uremic syndrome (D(+)HUS) is the most common cause of acute renal failure among children. Renal damage in D(+)HUS is caused by Shiga toxin (Stx), which is elaborated by Shigella dysenteriae and certain strains of Escherichia coli, in North America principally E coli O15...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2981485/ https://ncbi.nlm.nih.gov/pubmed/20644116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-02-271957 |
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