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Intermediates can accelerate protein folding

The effect of intermediates on the rate of protein folding is explored by applying Kramers’ theory of diffusive barrier crossing in the high friction limit. Intermediates are represented as local minima in the transition barrier. We observe that very large or very small additional barriers created b...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wagner, Clemens, Kiefhaber, Thomas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences 1999
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC21981/
https://ncbi.nlm.nih.gov/pubmed/10359778
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