Detection of residue contacts in a protein folding intermediate

Protein folding can be described in terms of the development of specific contacts between residues as a highly disordered polypeptide chain converts into the native state. Here we describe an NMR based strategy designed to detect such contacts by observation of nuclear Overhauser effects (NOEs). Exp...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Balbach, Jochen, Forge, Vincent, Lau, Wai Shun, Jones, Jonathan A., van Nuland, Nico A. J., Dobson, Christopher M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23785/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9207065/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.14.7182
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