Transient aggregates in protein folding are easily mistaken for folding intermediates
It has been questioned recently whether populated intermediates are important for the protein folding process or are artefacts trapped in nonproductive pathways. We report here that the rapidly formed intermediate of the spliceosomal protein U1A is an off-pathway artefact caused by transient aggrega...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21005/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9177173/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.12.6084 |
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