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Transient aggregates in protein folding are easily mistaken for folding intermediates

It has been questioned recently whether populated intermediates are important for the protein folding process or are artefacts trapped in nonproductive pathways. We report here that the rapidly formed intermediate of the spliceosomal protein U1A is an off-pathway artefact caused by transient aggrega...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Silow, Maria, Oliveberg, Mikael
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences of the USA 1997
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC21005/
https://ncbi.nlm.nih.gov/pubmed/9177173
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