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Simulation, experiment, and evolution: Understanding nucleation in protein S6 folding

In this study, we explore nucleation and the transition state ensemble of the ribosomal protein S6 using a Monte Carlo (MC) Go model in conjunction with restraints from experiment. The results are analyzed in the context of extensive experimental and evolutionary data. The roles of individual residu...

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Библиографические подробности
Главные авторы: Hubner, Isaac A., Oliveberg, Mikael, Shakhnovich, Eugene I.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2004
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC420398/
https://ncbi.nlm.nih.gov/pubmed/15150413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401672101
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