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The ensemble folding kinetics of protein G from an all-atom Monte Carlo simulation

Protein G is folded with an all-atom Monte Carlo simulation by using a Gō potential. When folding is monitored by using burial of the lone tryptophan in protein G as the reaction coordinate, the ensemble kinetics is single exponential. Other experimental observations, such as the burst phase and mut...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Shimada, Jun, Shakhnovich, Eugene I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2002
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123229/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12165568/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.162268099
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