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A structure-based method for derivation of all-atom potentials for protein folding

A method for deriving all-atom protein folding potentials is presented and tested on a three-helix bundle protein, as well as on hairpin and helical sequences. The potentials obtained are composed of a contact term between pairs of atoms, and a local density term for each atom, mimicking solvent exp...

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Detalhes bibliográficos
Main Authors: Kussell, Edo, Shimada, Jun, Shakhnovich, Eugene I.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122771/
https://ncbi.nlm.nih.gov/pubmed/11943859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.072665799
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