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The Ensemble Folding Kinetics of the FBP28 WW Domain Revealed by an All-atom Monte Carlo Simulation in a Knowledge-based Potential

In this work, we apply a detailed all-atom model with a transferable knowledge-based potential to study the folding kinetics of Formin-Binding protein, FBP28, which is a canonical three-stranded β-sheet WW domain. Replica exchange Monte Carlo (REMC) simulations starting from random coils find native...

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Autori principali: Xu, Jiabin, Huang, Lei, Shakhnovich, Eugene I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092795/
https://ncbi.nlm.nih.gov/pubmed/21365688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22993
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