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Folding, Misfolding, and Amyloid Protofibril Formation of WW Domain FBP28
We study the folding mechanism of a triple β-strand WW domain from the Formin binding protein 28 (FBP28) at atomic resolution with explicit water model using replica exchange molecular dynamics computer simulations. Extended sampling over a wide range of temperatures to obtain the free energy, entha...
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| Main Authors: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Biophysical Society
2006
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1459504/ https://ncbi.nlm.nih.gov/pubmed/16533840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.076406 |
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