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The role of the turn in β-hairpin formation during WW domain folding

The folding of WW domains is rate limited by formation of a β-hairpin comprising residues from strands 1 and 2. Residues in the turn of this hairpin have reported Φ-values for folding close to 1 and have been proposed to nucleate folding. High Φ-values do not necessarily imply that the energetics of...

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Bibliografske podrobnosti
Main Authors: Sharpe, Tim, Jonsson, Amanda L., Rutherford, Trevor J., Daggett, Valerie, Fersht, Alan R.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2204123/
https://ncbi.nlm.nih.gov/pubmed/17766370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073004907
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