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Circular permutation of a WW domain: Folding still occurs after excising the turn of the folding-nucleating hairpin
A hyperstable Pin1 WW domain has been circularly permuted via excision of the fold-nucleating turn; it still folds to form the native three-strand sheet and hydrophobic core features. Multiprobe folding dynamics studies of the normal and circularly permuted sequences, as well as their constituent ha...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4051316/ https://ncbi.nlm.nih.gov/pubmed/24350581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja410824x |
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